My doc told me to get this. And it improved my blood panel and health overall as a regular supplement and guards against so many cognitive diseases and other problems. I’ll tell you what. Sometimes I get up early to let the dogs out and feel pretty zonked and like it might be a bad day... and have this sublingually then go back to bed. I wake up an hour or two later feeling amazing. So, that started when I started doing that. Now I look fwd to the 6am dog walk and another nap before I start my day.

I have histamine intolerance issues, which may be influenced by undermethylation. However, I don't tolerate methyl B12 well. I prefer sublingual B12 in the hydroxocobalamin form, but have only found 2500 mcg until now. I was concerned about reacting to the other ingredients, but so far, so good. I'll update if anything changes.

Have used this off and on for years. Love it for sure! It works for me and my hubby.<br />He had not been taking any B-12 ever. When he was tested, he was in range but<br />barely. He is 69yo. We need this particularly as we age or have health problems.

During two separate incidents involving low level cyanide/cyanogen exposure -- one caused by eating a giant bag of almonds in a few days, and another caused by running a powerful electric arc in air between two large graphite electrodes with insufficient ventilation -- this vitamin quickly resolved the obvious symptoms of minor cyanide poisoning.<br /><br />Improvements were apparent within a few minutes.<br /><br />The amount used was a few dozen tablets.<br /><br />Hydroxocobalamin is known to be safe and effective in doses of multiple grams for treating major cyanide exposure, so a hundred milligrams or so is undoubtedly safe as well -- and has clearly resolved two minor incidents in my experience.<br /><br />I do wish that it were easier to find even larger quantities of this substance for my chemical exposure first aid kit. I will keep looking. But in the meantime, this one tastes great, absorbs quickly, and shows clear effectiveness.

I have heterozygous genes that do better with methylcobalmin but I have homozygous genes that have difficulty with methyl donors-- so I have used other hydroxocobalmins for a couple of years, but with starting gabapentin, which depletes B12, I have needed a higher dose and this is a good price for higher dose. Recommend for those who cannot take methylcobalmin and do not want to take cyanocobalmin.

Does the job