While the product is good, the venor, Healthy Minded, did not send it in a cold pack, so I returned it. Here's what Pure Encapsulations says and requires when they fill an order: "Due to the heat sensitivity of this product, we will only ship orders containing this product on Mon-Wed. Please be advised that if you place your order on Thursday or Friday it will be held until Monday. All orders are shipped with freezer packs enclosed in 48 hour "cold-pack" insulated boxes." So check your vendor before spending this much money on it. Pure Encapsulations makes great products, but if the vendor doesn't follow the necessary protocol to protect the product, you won't get the benefit you would expect and deserve to get.

Pure encapsulations are just that: pure. So glad we found this line of products. My daughter and I have the MTHFR mutation, plus celiac and food allergies that include corn and soy. Our ingredient limitations mean it can be hard to find supplements and we really need probiotics and methylated vitamins.<br /><br />My husband, who also has some food allergies, got c.diff. after multiple rounds of strong antibiotics. The Pure Encapsulations probiotics plus a Solgar probiotic (listed below) are really helping. We intend to push probiotics heavily to lower the chance of c.diff. recurrence. (We also add in some homemade fermented foods, such as sauerkraut.)<br /><br />We use Pure Encapsulations for methyfolate, methylcobalamin, and multiple probiotics. No adverse reactions at all! Absolutely fantastic!<br /><br />For fighting C. diff:<br />While 40 days of Flagyl beat back the original C. diff, it threatened to return, and only massive amounts of probiotics drove it away completely and has kept it away. Lactobacillus rhamnosus GG and Saccharomyces boulardii are the two major probiotics proven scientifically to fight Clostridium difficile (C.diff) specifically.<br /><br />Advanced Multi-Billion Dophilus from Solgar is a must. This one of the very few probiotics I found that contained Lactobacillus rhamnosus GG, and it's the purest if you have a problem with food allergies.<br />http://smile.amazon.com/Advanced-Multi-Billion-Dophilus-60-VegCap/dp/B00028M4I6?ie=UTF8&ref_=cm_cr_ryp_prd_ttl_sol_10<br /><br />The following are Pure Encapsulations brand - high quality and pure:<br /> Saccharomyces boulardii (if you order from Pureformulas.com, it will come refrigerated which is important)<br /> Lactobacillus Sporogenes (also spore-based)<br /> http://smile.amazon.com/Pure-Encapsulations-Lactobacillus-Hypoallergenic-Refrigeration/dp/B002HY63TO?ie=UTF8&psc=1&redirect=true&ref_=oh_aui_search_detailpage<br /> Probiotic G.I.<br /> http://smile.amazon.com/Pure-Encapsulations-Probiotic-Function-Intestinal/dp/B003GCGM0Q?ie=UTF8&psc=1&redirect=true&ref_=oh_aui_search_detailpage<br /><br />Between these various probiotics, we get a tremendous coverage of a wide range of probiotic strains. I had also used prescription probiotics, but I believe these work more effectively with a much wider coverage than the prescription probiotic (which was very limited in coverage and did not include Lactobacillus rhamnosus GG or Saccharomyces boulardii).

I have had bloating and reflux for years...I read that this strain of probiotic prevents SIBO...my symptoms have definately improved and I have not eve, finished the first bottle (60 capsules)

Had a very bad c-diff bacterial infection and no anti-biotic touched it. Read that this particular probiotic helped tackle it. Took these for a little over a month and then started seeing a difference. I'm going to send this info to my doctor because I think everyone with c-diff should be taking these.

I don't know... I would have probably loved it but the company irresponsibly packed it against label instructions with our an ice pack as it is supposed to be refrigerated.

Will never purchase from this store again. Thus product was supposed to be refrigerated and it wasn't. The product was just thrown in a box and shipped. Expensive product that I needed. Very upset.